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Op-Ed: Iboga, Ibogaine & 5-MeO-DMT: What gets missed when complex medicines are reduced to standard protocols

By Paije West and Fletcher Burdick
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Ibogaine, the alkaloid derived from the Tabernanthe iboga plant, and often through a more sustainable option voacanga africana, is front and center, riding the third wave of the modern psychedelic movement.

We hear of miracle stories: opiate withdrawals vanishing into thin air, neurotransmitters reset, an injured brain healing, trauma stored in the body and mind fresh with new perspective. But what happens when we not only extract a single alkaloid from a master plant, but also extract context, culture and tradition? As these medicines move towards standardization, we risk confusing safety with completeness.

The lesser known full-spectrum iboga, a perennial shrub found in Gabon, Cameroon and the Congo basin of Central Africa, is a root bark with a complex profile of alkaloids working in a powerful symbiosis. Iboga is a sacrament of the Bwiti tradition, a spiritual system with many branches practiced in the villages of the forest.

One might even say that working with iboga is akin to listening to a full symphony, an orchestra of sensation and sound, while the extracted, often semi-synthetic, ibogaine is like hearing a singular, transformative note. Clinical ibogaine has an essential role in treating addiction and supporting people in critical moments of need. But when we mistake the molecule for the entirety of the medicine, something important gets lost.

The Bwiti teach about truth, strength and resilience. The tradition is rooted in animism, honoring the wisdom of all beings, plants, animals and material. It is important to name that Indigenous knowledge, like most spiritual systems, is ideally worked with through an internal knowing and connection to community, and less so when placed on a pedestal, or through guru-ification of a singular person, group or rigid ideology.

However, when iboga is removed from its cultural roots, something essential goes missing that is not easily replaced by training, intention or clinical framing. In its traditional context, iboga is not a drug or even a plant; it is a living consciousness that requires relationship much like any human being would. It is held within lineage, ritual, community and a system of meaning that shapes both the experience and what follows it. Without that living framework, the experience can become untethered. What remains is often a powerful and disorienting pharmacological event that lacks the relational and symbolic anchors that help a person metabolize what they encounter.

Some believe that iboga should not be separated from the Bwiti tradition, but what does this actually mean for both western iboga providers and ibogaine clinics? Many iboga providers travel for initiation, rites of passage, and the observation and witnessing of Bwiti elders. They make their way home to the western world, serving as bridge people. Some providers honor the tradition while also allowing for the reality of the modern mind, nervous system and experience. Others attempt to replicate an Indigenous ceremony without lineage, creating confusion and appropriating what is not theirs to carry.

Ibogaine clinics tend to focus on the properties of ibogaine, and less so its cultural roots. While the presence of medics, therapists and a contained, well-supported environment is vital, we cannot forget where the medicine comes from. The land, the elders and the tradition are integral to the medicine itself. 

It is less often we see earth-based traditions or Indigenous voices, teachings, or students of elders brought into clinical spaces. With the rise in popularity of ibogaine, we are seeing more clinics serve as revolving doors, with extended waitlists and missing context for what a participant just experienced.

Ceremonial wisdom sees each person as an individual expression of nature. Without truly honoring lineage and elders through a living bridge of connection, not just a reciprocity check or week in Gabon, we are missing an imperative aspect of the work.

In western settings there is often an attempt to compensate for this loss through structure and protocol. While structure has value, it can give a false sense of completeness—iboga and ibogaine are not self-explanatory.

Without a cultural framework that contextualizes memory, identity and potential psychological rupture, participants may leave with insights that are difficult to integrate or in some cases destabilizing. The absence of context can also shift the power dynamic in subtle ways, placing more interpretive authority in the hands of facilitators, who may not be rooted in a relationship with a lineage that has stewarded this master plant for generations.

Efforts to legalize ibogaine have accelerated in recent years. Colorado’s ibogaine bill HB26-1325 includes “benefit-sharing” language with Bwiti communities, though in practice this remains largely symbolic and difficult to quantify. Could the focus on a single alkaloid be driven less by the medicine itself and more by what can be patented and standardized? 

When medicines are reduced to their pharmacological components, it becomes easier to treat them as modular tools that can be sequenced and optimized through protocol. The rise of ibogaine and 5-MeO-DMT stacking is an example of how standardization can both support and undermine safety. 

The increasingly common sequencing of ibogaine, often delivered without traditional context, followed by 5-MeO-DMT—an extremely expansive psychedelic that produces a powerful nondual experience, warrants pause and attention.

There is a tendency to assume that because 5-MeO-DMT often produces short non-narrative experiences, it is simpler to administer. This assumption can lead to an underestimation of both the intensity and the aftermath, particularly when stacked with ibogaine or iboga. Individuals can emerge from these sessions with a profound shift in perception that requires careful support as well as community integration.

When care is overly protocol-driven there is a risk that facilitators miss key signals or move too quickly through stages that need more time and attunement. What is gained in efficiency can be lost in precision.

On one hand, the development of protocols has helped reduce certain acute risks. Clear screening processes, dosing guidelines, and medical oversight have brought a level of consistency to an otherwise unpredictable space. On the other hand, the drive toward standardization can flatten the complexity of the experience and the people undergoing it. A protocol can account for physiological and psychological variables. But can it fully account for readiness, relational dynamics, the spiritual field, or the subtle ways in which a person’s history interacts with the medicine?

Individualized care, whether in clinical or ceremonial settings, does not mean the absence of structure; it means that structure remains responsive and relational rather than rigid and extractive. It requires facilitators to develop a high level of sensitivity to each participant to understand when to follow a guideline and when to deviate from it. The benefits of this approach include a greater capacity to meet people where they are and to reduce the likelihood of adverse outcomes that arise from misalignment. The risks are that it demands more experience, more accountability, and a willingness to operate without the safety net of a one-size-fits-all model.

The alternative is not the absence of structure, but structure in service to relationship. Protocols that remain flexible, responsive and grounded in the individual rather than fixed sequences applied uniformly. When they are treated as living frameworks rather than fixed formulas, structures and systems can support both safety and depth. When they become substitutes for judgment and relationship they can blur the very complexities they are meant to manage. Do they remain in service to the person, or slowly begin to replace the very awareness that keeps the work safe?

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About the Authors

Paije West and Fletcher Burdick

Paije Alexandra West is the founder of ETÉREO Baja, with over a decade of experience as a psychedelic guide and retreat leader. Her work bridges Indigenous ceremonial lineages with trauma-informed, integration-first care. Paije has trained in somatic healing, Internal Family Systems, harm reduction, and birthwork, and has supported preparation and aftercare for individuals at ibogaine clinics. She is Bwiti-initiated in Gabon, completing Missoko initiation, Nyembe rites, and a second initiation at the Fang Ntann village.

Fletcher Welsh Burdick is co-founder of ETÉREO Baja, a Q’ero-initiated facilitator and substance-use specialist trained with Indigenous teachers in Peru. Drawing from lived recovery and lineage-based training, he supports guests through ceremonial care, integration, and harm-reduction frameworks, blending Andean energy medicine, somatic awareness, and modern recovery principles.