Research

Dr Simon Ruffell – Other Ways of Knowing

May 13, 2025
Featuring: Dr Simon Ruffell

In this episode of Psychedelics Today, Joe Moore speaks with Dr. Simon Ruffell, a psychiatrist from London who is also training in the Shipibo healing tradition of the Peruvian Amazon. After working in psychiatry for years, Dr. Ruffell began to feel frustrated with the limits of modern treatments. As a result, he turned to plant medicine and Indigenous healing.

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In this episode of Psychedelics Today, Joe Moore speaks with Dr. Simon Ruffell, a psychiatrist from London who is also training in the Shipibo healing tradition of the Peruvian Amazon. After working in psychiatry for years, Dr. Ruffell began to feel frustrated with the limits of modern treatments. As a result, he turned to plant medicine and Indigenous healing.

Throughout the episode, Dr. Ruffell shares how Western psychiatry and traditional medicine can work together. He explains the Shipibo idea that illness shows up on three levels: spiritual, emotional, and physical. Healing, he says, must reach all three. Moreover, he describes how ignoring these levels—especially in psychedelic work—can lead to harm.

Dr. Ruffell also discusses the importance of training, trust, and cross-cultural respect. He believes that blending Indigenous and Western methods may lead to safer and more effective psychedelic care. To support this, he founded Onaya Science and Onaya.io, which work closely with Amazonian healers. Notably, their early research with military veterans is showing strong results. In fact, 84% of participants no longer met the criteria for PTSD six months after treatment.

This conversation is both thoughtful and practical. If you’re a therapist, researcher, or someone exploring psychedelic healing, you’ll find insights here. Dr. Ruffell reminds us that we don’t need to choose between science and spirit. Instead, we can learn from both.

https://www.drsimonruffell.com/

https://www.onaya.io/

https://onaya.science/

PT 603 - Dr Simon Ruffell

Other Ways of Knowing

Dr Simon Ruffell

Dr. Simon Ruffell is a psychiatrist, researcher, and student of curanderismo who bridges Western medicine with Indigenous healing traditions. He holds an MBChB, MRCPsych, and a PhD in ayahuasca and mental health outcomes. Dr. Ruffell has contributed to major psychedelic studies, including psilocybin trials at King’s College London. As CEO of Onaya and co-founder of Onaya Science, he collaborates with Amazonian communities to study ayahuasca’s therapeutic potential in naturalistic settings. He is currently training in Shipibo shamanism under Don Rono Lopez, aiming to integrate scientific and spiritual paradigms in mental health care.