Psychology

Understanding Bad Trips: The Power and Potential of Adverse Psychedelic Experiences

July 23, 2024
Featuring: Erica Rex, MA

What are bad trips, or adverse, negative, or challenging experiences? Can a definition truly define the power they have to create intense distress and sometimes life-defining moments? Why do they happen, and how do you deal with them?

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What are bad trips, or adverse, negative, or challenging experiences? Can a definition truly define the power they have to create intense distress and sometimes life-defining moments? Why do they happen, and how do you deal with them?

In this episode, Joe interviews Erica Rex, MA: award-winning journalist, past guest, thought leader on psychedelic medicine, and participant in one of the first clinical trials using psilocybin to treat cancer-related depression.

She tells the story of her recent harrowing experience, brought on by 6 times the amount of Syrian rue that was recommended: from entities threatening her, to a sense of terror she was going to die, to finding her way out of it with time, and most importantly, context to process and a strong support system. She and Joe emphasize the reality that bad trips can happen at any time, with any dose, for any reason, and that – if you can make your way through the experience without being traumatized – you can learn a lot about yourself during those states.

Her book, “The Heroine’s Journey: a woman’s quest for sanity in the psychedelic age” will be published by She Writes Press in the spring of 2026.

She discusses:

  • Methods to help others having a bad experience
  • Her skepticism about psychedelic therapy being in a medical context at all
  • Her thoughts on the recent ICER recommendation against approving MDMA and the multiple topics not addressed
  • Possible complications from MDMA use nobody talks about, from cytotoxic effects to even sudden-onset psychosis
  • The pathologizing of anything outside the ordinary, to the point that we’re trying to suppress natural human emotions and reactions

and more!

Links

Psychedelicrenaissance.substack.com

National Institutes of Health/National Cancer Institute: A Breast Cancer Patient’s Perspectives on the Uses of Psychedelics in Medicine (Erica’s talk starts at 1:04:41 and lasts about 44 minutes)

PT273 – Erica Rex – Clinical Trials and Spontaneous Mystical Experiences

PT409 – Pathology, The DSM, and The Ontological Shock of Psychedelic Experiences, featuring: Erica Rex & Mona Sobhani, Ph.D.

YouTube: PT Live: Joe Moore, Erica Rex, and Vincent Verroust Discuss French Psychedelic History and More

Could the Sonoran Desert Toad Cure Narcissism? by Erica Rex

Chacruna.net: DEA Denies Soul Quest’s Religious Exemption: Impacts on the Ayahuasca Community

An Inside Look at the FDA and Early Drug Development, featuring: Dr. Amanda Holley

Icer.org: Institute for Clinical and Economic Review Releases Draft Evidence Report on Treatment for Post-Traumatic Stress Disorder

Lykospbc.com: Lykos Therapeutics Statement on FDA Advisory Committee Meeting

Springer.com: Evaluation of Cytotoxic, Necrotic, Apoptotic, and Autophagic Effects of Methamphetamine and 3,4-Methylenedioxymethamphetamine on U-87 MG (Glial) and B104-1–1 (Neuronal) Cell Lines

Nih.gov: Persistent Psychosis After a Single Ingestion of “Ecstasy” (MDMA)

Goodreads.com: Albert Camus’ quote about suicide

Castaliafoundation.com: MDMA Solo

Firesideproject.org

Imdb.com: Get Him to the Greek

Le Canicule

In this Episode

Erica Rex, MA

Erica Rex is an award-winning journalist with degrees from Stanford University and Brown University. She was a Bollinger Science Journalism Fellow at Columbia University Graduate School of Journalism. She brings 30 years of medical and journalistic experience to the world of psychedelic medicine. She is embedded in the field of psychedelic research and writing on the re-emergence of psychedelic medicine for prestigious publications such as Scientific American, The New York Times, The Times (UK), The Independent, Mad in America, and Psychedelics Today. She is affiliated with top researchers in the field in the UK, the US, and France. As both patient and thought leader on psychedelic medicine, she gives invited talks about her experience to professional conferences and federal agencies, such as the National Institutes of Health. She has been interviewed on NPR, Sky News, and many other news outlets. Her work lends a unique female perspective to the male-dominated field of psychedelic medicine, telling the story of psychedelics from two perspectives: patient/subject and highly accomplished science journalist, and CPTSD survivor. Her book-in-progress, The Heroine’s Journey: A Woman’s Quest for Sanity in the Psychedelic Age, weaves together memoir, narrative journalism and science, and traces the story of psychedelics through the lens of her quest to heal from childhood trauma. She is represented by HighSpot Literary.

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Photo of Erica Rex by Pete Kiehart